Structure of the Lectin Mannose 6-Phosphate Receptor Homology (MRH) Domain of Glucosidase II, an Enzyme That Regulates Glycoprotein Folding Quality Control in the Endoplasmic Reticulum

Here we report for the first time the three-dimensional structure of a mannose 6-phosphate receptor homology (MRH) domain present in a protein with enzymatic activity, glucosidase II (GII). GII is involved in glycoprotein folding in the endoplasmic reticulum. GII removes the two innermost glucose re...

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Autors principals: Olson, Linda J., Orsi, Ramiro, Alculumbre, Solana G., Peterson, Francis C., Stigliano, Ivan D., Parodi, Armando J., D'Alessio, Cecilia, Dahms, Nancy M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
Matèries:
Glycobiology and Extracellular Matrices
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675582/
https://ncbi.nlm.nih.gov/pubmed/23609449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.450239
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