Influence of CYP2D6 Polymorphisms on Serum Levels of Tamoxifen Metabolites in Spanish Women with Breast Cancer

Background Estrogen receptor-positive breast cancer tumors depend on estrogen signaling for their growth and replication and can be treated by anti-estrogen therapy with tamoxifen. Polymorphisms of the CYP2D6 and CYP2C19 genes are associated with an impaired response to tamoxifen. The study objectiv...

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Detalhes bibliográficos
Main Authors: Zafra-Ceres, Mercedes, de Haro, Tomas, Farez-Vidal, Esther, Blancas, Isabel, Bandres, Fernando, de Dueñas, Eduardo Martinez, Ochoa-Aranda, Enrique, Gomez-Capilla, Jose A., Gomez-Llorente, Carolina
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2013
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Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675507/
https://ncbi.nlm.nih.gov/pubmed/23781139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.5708
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