Large Sample Size, Wide Variant Spectrum, and Advanced Machine-Learning Technique Boost Risk Prediction for Inflammatory Bowel Disease

We performed risk assessment for Crohn’s disease (CD) and ulcerative colitis (UC), the two common forms of inflammatory bowel disease (IBD), by using data from the International IBD Genetics Consortium’s Immunochip project. This data set contains ∼17,000 CD cases, ∼13,000 UC cases, and ∼22,000 contr...

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Autores principales: Wei, Zhi, Wang, Wei, Bradfield, Jonathan, Li, Jin, Cardinale, Christopher, Frackelton, Edward, Kim, Cecilia, Mentch, Frank, Van Steen, Kristel, Visscher, Peter M., Baldassano, Robert N., Hakonarson, Hakon
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675261/
https://ncbi.nlm.nih.gov/pubmed/23731541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2013.05.002
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