Angiotensin II Type 1 Receptor Antagonist Attenuates Lacrimal Gland, Lung, and Liver Fibrosis in a Murine Model of Chronic Graft-Versus-Host Disease

Chronic graft-versus-host disease (cGVHD), a serious complication following allogeneic HSCT (hematopoietic stem cell transplantation), is characterized by systemic fibrosis. The tissue renin-angiotensin system (RAS) is involved in the fibrotic pathogenesis, and an angiotensin II type 1 receptor (AT1...

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Main Authors: Yaguchi, Saori, Ogawa, Yoko, Shimmura, Shigeto, Kawakita, Tetsuya, Hatou, Shin, Satofuka, Shingo, Nakamura, Shigeru, Imada, Toshihiro, Miyashita, Hideyuki, Yoshida, Satoru, Yaguchi, Tomonori, Ozawa, Yoko, Mori, Takehiko, Okamoto, Shinichiro, Kawakami, Yutaka, Ishida, Susumu, Tsubota, Kazuo
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675140/
https://ncbi.nlm.nih.gov/pubmed/23762250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064724
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