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Sequence specificity of point mutations induced during passage of a UV-irradiated shuttle vector plasmid in monkey cells.

A simian virus 40-based shuttle vector was used to characterize UV-induced mutations generated in mammalian cells. The small size and placement of the mutagenesis marker (the supF suppressor tRNA gene from Escherichia coli) within the vector substantially reduced the frequency of spontaneous mutatio...

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Udgivet i:Mol Cell Biol
Principais autores: Hauser, J, Seidman, M M, Sidur, K, Dixon, K
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1986
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC367508/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3537686/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.6.1.277-285.1986
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