Campath, calcineurin inhibitor reduction and chronic allograft nephropathy (3C) study: background, rationale, and study protocol

BACKGROUND: Kidney transplantation is the best treatment for patients with end-stage renal failure, but uncertainty remains about the best immunosuppression strategy. Long-term graft survival has not improved substantially, and one possible explanation is calcineurin inhibitor (CNI) nephrotoxicity....

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Main Authors: Haynes, Richard, Baigent, Colin, Harden, Paul, Landray, Martin, Akyol, Murat, Asderakis, Argiris, Baxter, Alex, Bhandari, Sunil, Chowdhury, Paramit, Clancy, Marc, Emberson, Jonathan, Gibbs, Paul, Hammad, Abdul, Herrington, Will, Jayne, Kathy, Jones, Gareth, Krishnan, Nithya, Lay, Michael, Lewis, David, Macdougall, Iain, Nathan, Chidambaram, Neuberger, James, Newstead, Chas, Pararajasingam, Ravi, Puliatti, Carmelo, Rigg, Keith, Rowe, Peter, Sharif, Adnan, Sheerin, Neil, Sinha, Sanjay, Watson, Chris, Friend, Peter
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2013
Teme:
Clinical Trial Protocol
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674985/
https://ncbi.nlm.nih.gov/pubmed/23641902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2047-1440-2-7
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