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Mosaicism in Stickler syndrome

Stickler syndrome is a heterogeneous condition due to mutations in COL2A1, COL11A1, COL11A2, and COL9A1. To our knowledge, neither non-penetrance nor mosaicism for COL2A1 mutations has been reported for Stickler syndrome. We report on a family with two clinically affected sibs with Stickler syndrome...

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Autors principals: Stevenson, David A., Vanzo, Rena, Damjanovich, Kristy, Hanson, Heather, Muntz, Harlan, Hoffman, Robert O., Bayrak-Toydemir, Pinar
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674818/
https://ncbi.nlm.nih.gov/pubmed/22522174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmg.2012.03.006
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