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Two antagonistic clock-regulated histidine kinases time the activation of circadian gene expression

The cyanobacterial circadian pacemaker consists of a three-protein clock – KaiA, KaiB and KaiC – that generates oscillations in the phosphorylation state of KaiC. Here we investigate how temporal information encoded in KaiC phosphorylation is transduced to RpaA, a transcription factor required for c...

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Autori principali: Gutu, Andrian, O’Shea, Erin K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674810/
https://ncbi.nlm.nih.gov/pubmed/23541768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.02.022
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