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Temporal requirement for SMN in motoneuron development

Proper function of the motor unit is dependent upon the correct development of dendrites and axons. The infant/childhood onset motoneuron disease spinal muscular atrophy (SMA), caused by low levels of the survival motor neuron (SMN) protein, is characterized by muscle denervation and paralysis. Alth...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hao, Le T., Duy, Phan Q., Jontes, James D., Wolman, Marc, Granato, Michael, Beattie, Christine E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674802/
https://ncbi.nlm.nih.gov/pubmed/23459934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt110
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