γ-Irradiation–Induced DNA Damage Checkpoint Activation Involves Feedback Regulation between Extracellular Signal-Regulated Kinase 1/2 and BRCA1

Previous studies from our laboratory have shown that the activation of G(2)-M checkpoint after exposure of MCF-7 breast cancer cells to γ-irradiation (IR) is dependent on the activation of extracellular signal-regulated kinase 1/2 (ERK1/2) signaling. Studies presented in this report indicate that IR...

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Bibliografiset tiedot
Päätekijät: Yan, Ying, Black, Claudine P., Cao, Phu T., Haferbier, Jamie L., Kolb, Ryan H., Spieker, Rebecca S., Ristow, Alexandra M., Cowan, Kenneth H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2008
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674789/
https://ncbi.nlm.nih.gov/pubmed/18593910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-5818
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