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SF3B1 mutations in chronic lymphocytic leukemia

SF3B1 is a critical component of the splicing machinery, which catalyzes the removal of introns from precursor messenger RNA (mRNA). Next-generation sequencing studies have identified mutations in SF3B1 in chronic lymphocytic leukemia (CLL) at high frequency. In CLL, SF3B1 mutation is associated wit...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Wan, Youzhong, Wu, Catherine J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674664/
https://ncbi.nlm.nih.gov/pubmed/23568491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-02-427641
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