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SF3B1 mutations in chronic lymphocytic leukemia
SF3B1 is a critical component of the splicing machinery, which catalyzes the removal of introns from precursor messenger RNA (mRNA). Next-generation sequencing studies have identified mutations in SF3B1 in chronic lymphocytic leukemia (CLL) at high frequency. In CLL, SF3B1 mutation is associated wit...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society of Hematology
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3674664/ https://ncbi.nlm.nih.gov/pubmed/23568491 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-02-427641 |
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