Deletion of interferon-γ delays onset and severity of dacryoadenitis in CD25KO mice

INTRODUCTION: To investigate the role of interferon-gamma (IFN-γ) in the onset and severity of dacryoadenitis in the CD25 knockout (KO) mouse model of Sjögren Syndrome. METHODS: CD25/IFN-γ double KO (γDKO) mice were created by crossbreeding CD25KO and IFN-γKO mice. Mice were used at 8, 12, and 16 we...

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Detalhes bibliográficos
Main Authors: Pelegrino, Flavia SA, Volpe, Eugene A, Gandhi, Niral B, Li, De-Quan, Pflugfelder, Stephen C, de Paiva, Cintia S
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674599/
https://ncbi.nlm.nih.gov/pubmed/23116218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4077
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