KCNA5 gene is not confirmed as a systemic sclerosis-related pulmonary arterial hypertension genetic susceptibility factor

INTRODUCTION: Potassium voltage-gated channel shaker-related subfamily member 5 (KCNA5) is implicated in vascular tone regulation, and its inhibition during hypoxia produces pulmonary vasoconstriction. Recently, a protective association of the KCNA5 locus with systemic sclerosis (SSc) patients with...

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Autori principali: Bossini-Castillo, Lara, Simeon, Carmen P, Beretta, Lorenzo, Broen, Jasper, Vonk, Madelon C, Callejas, José Luis, Carreira, Patricia, Rodríguez-Rodríguez, Luis, García-Portales, Rosa, González-Gay, Miguel A, Castellví, Ivan, Camps, María Teresa, Tolosa, Carlos, Vicente-Rabaneda, Esther, Egurbide, María Victoria, Schuerwegh, Annemie J, Hesselstrand, Roger, Lunardi, Claudio, van Laar, Jacob M, Shiels, Paul, Herrick, Ariane, Worthington, Jane, Denton, Christopher, Radstake, Timothy RDJ, Fonseca, Carmen, Martin, Javier
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674598/
https://ncbi.nlm.nih.gov/pubmed/23270786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4124
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