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Novel Diagnostic Paradigms for Friedreich Ataxia

Friedreich ataxia is the most common inherited ataxia, with a wide phenotypic spectrum. It is generally caused by GAA expansions on both alleles of FXN, but a small percentage of patients are compound heterozygotes for a pathogenic expansion and a point mutation. Two recent diagnostic innovations ar...

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Hlavní autoři: Brigatti, Karlla W., Deutsch, Eric C., Lynch, David R., Farmer, Jennifer M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674546/
https://ncbi.nlm.nih.gov/pubmed/22752491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0883073812448440
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