FBW7 regulates endothelial functions by targeting KLF2 for ubiquitination and degradation

F-box and WD repeat domain-containing 7 (FBW7), the substrate-binding subunit of E3 ubiquitin ligase SCF(FBW7) (a complex of SKP1, cullin-1 and FBW7), plays important roles in various physiological and pathological processes. Although FBW7 is required for vascular development, its function in the en...

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Bibliografiska uppgifter
Huvudupphovsmän: Wang, Rui, Wang, Yan, Liu, Ning, Ren, Chunguang, Jiang, Cong, Zhang, Kai, Yu, Su, Chen, Yunfei, Tang, Hui, Deng, Qi, Fu, Cong, Wang, Yingcong, Li, Rong, Liu, Mingyao, Pan, Weijun, Wang, Ping
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2013
Ämnen:
Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674386/
https://ncbi.nlm.nih.gov/pubmed/23507969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2013.42
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