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Connexin 43 impacts on mitochondrial potassium uptake
In cardiomyocytes, connexin 43 (Cx43) forms gap junctions and unopposed hemichannels at the plasma membrane, but the protein is also present at the inner membrane of subsarcolemmal mitochondria (SSM). Both inhibition and genetic ablation of Cx43 reduce ADP-stimulated complex 1 respiration. Since mit...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Frontiers Media S.A.
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3674322/ https://ncbi.nlm.nih.gov/pubmed/23760924 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2013.00073 |
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