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Lck tyrosine kinase mediates β1-integrin signalling to regulate Schwann cell migration and myelination

The interaction between laminin and β1-integrin on the surface of Schwann cells regulates Schwann cell proliferation, maturation and differentiation. However, the signalling mediators that fine-tune these outcomes are not fully elucidated. Here we show that lymphoid cell kinase is the crucial effect...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ness, Jennifer K., Snyder, Kristin M., Tapinos, Nikos
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Pub. Group 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674276/
https://ncbi.nlm.nih.gov/pubmed/23715271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2928
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