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Clonal evolution, genomic drivers and effects of therapy in chronic lymphocytic leukemia

PURPOSE: The identification of gene mutations and structural genomic aberrations that are critically involved in CLL pathogenesis is still evolving. One may postulate that genomic driver lesions with effects on CLL cell proliferation, apoptosis thresholds or chemotherapy resistance should increase i...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Ouillette, Peter, Saiya-Cork, Kamlai, Seymour, Erlene, Li, Cheng, Shedden, Kerby, Malek, Sami N.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674194/
https://ncbi.nlm.nih.gov/pubmed/23620403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-0138
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