Interaction between p53 and estradiol pathways in transcriptional responses to chemotherapeutics

Estrogen receptors (ERs) and p53 can interact via cis-elements to regulate the angiogenesis-related VEGFR-1 (FLT1) gene, as we reported previously. Here, we address cooperation between these transcription factors on a global scale. Human breast adenocarcinoma MCF7 cells were exposed to single or com...

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Autori principali: Lion, Mattia, Bisio, Alessandra, Tebaldi, Toma, De Sanctis, Veronica, Menendez, Daniel, Resnick, Michael A., Ciribilli, Yari, Inga, Alberto
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674086/
https://ncbi.nlm.nih.gov/pubmed/23518503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.24309
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