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Cigarette smoke induces methylation of the tumor suppressor gene NISCH

We have previously identified a putative tumor suppressor gene, NISCH, whose promoter is methylated in lung tumor tissue as well as in plasma obtained from lung cancer patients. NISCH was observed to be more frequently methylated in smoker lung cancer patients than in non-smoker lung cancer patients...

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Bibliografische gegevens
Hoofdauteurs: Ostrow, Kimberly Laskie, Michalidi, Christina, Guerrero-Preston, Rafael, Hoque, Mohammad O., Greenberg, Alissa, Rom, William, Sidransky, David
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Landes Bioscience 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674047/
https://ncbi.nlm.nih.gov/pubmed/23503203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.24195
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