Cigarette smoke induces methylation of the tumor suppressor gene NISCH

We have previously identified a putative tumor suppressor gene, NISCH, whose promoter is methylated in lung tumor tissue as well as in plasma obtained from lung cancer patients. NISCH was observed to be more frequently methylated in smoker lung cancer patients than in non-smoker lung cancer patients...

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Detalhes bibliográficos
Main Authors: Ostrow, Kimberly Laskie, Michalidi, Christina, Guerrero-Preston, Rafael, Hoque, Mohammad O., Greenberg, Alissa, Rom, William, Sidransky, David
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674047/
https://ncbi.nlm.nih.gov/pubmed/23503203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.24195
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