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Safeguarding clinical translation of pluripotent stem cells with suicide genes

The generation of human induced pluripotent stem cells (hiPSCs) opens a new avenue in regenerative medicine. However, transplantation of hiPSC-derived cells carries a risk of tumor formation by residual pluripotent stem cells. Numerous adaptive strategies have been developed to prevent or minimize a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Li, Weiqiang, Xiang, Andy Peng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674039/
https://ncbi.nlm.nih.gov/pubmed/23511011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/org.24317
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