Neural Precursor Cells Cultured at Physiologically Relevant Oxygen Tensions Have a Survival Advantage Following Transplantation

Traditionally, in vitro stem cell systems have used oxygen tensions that are far removed from the in vivo situation. This is particularly true for the central nervous system, where oxygen (O(2)) levels range from 8% at the pia to 0.5% in the midbrain, whereas cells are usually cultured in a 20% O(2)...

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Detalles Bibliográficos
Main Authors: Stacpoole, Sybil R.L., Webber, Daniel J., Bilican, Bilada, Compston, Alastair, Chandran, Siddharthan, Franklin, Robin J.M.
Formato: Artigo
Idioma:Inglês
Publicado: AlphaMed Press 2013
Assuntos:
Tissue Engineering and Regenerative Medicine
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3673758/
https://ncbi.nlm.nih.gov/pubmed/23677643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2012-0144
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