Derivation of neural precursor cells from human ES cells at 3% O(2) is efficient, enhances survival and presents no barrier to regional specification and functional differentiation

In vitro stem cell systems traditionally employ oxygen levels that are far removed from the in vivo situation. This study investigates whether an ambient environment containing a physiological oxygen level of 3% (normoxia) enables the generation of neural precursor cells (NPCs) from human embryonic...

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Detalhes bibliográficos
Main Authors: Stacpoole, S R L, Bilican, B, Webber, D J, Luzhynskaya, A, He, X L, Compston, A, Karadottir, R, Franklin, R J M, Chandran, S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091847/
https://ncbi.nlm.nih.gov/pubmed/21274009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2010.171
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