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miR221/222 in Cancer: Their Role in Tumor Progression and Response to Therapy

MiRNAs are small non-coding RNAs of ~24 nt that can block mRNA translation and/or negatively regulate its stability. There is a large body of evidence that dysregulation of miRNAs is a hallmark of cancer. miRNAs are often aberrantly expressed and their function is linked to the regulation of oncogen...

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Autors principals: Garofalo, M., Quintavalle, C., Romano, G., Croce, C.M., Condorelli, G.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3673714/
https://ncbi.nlm.nih.gov/pubmed/22082479
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