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Inhibition of Grb2-mediated activation of MAPK signal transduction suppresses NOR(1)/CB1954-induced cytotoxicity in the HepG2 cell line
The nitroreductase oxidored-nitro domain containing protein 1 (NOR(1)) gene may be involved in the chemical carcinogenesis of hepatic cancer and nasopharyngeal carcinoma (NPC). We have previously demonstrated that NOR(1) overexpression is capable of converting the monofunctional alkylating agent 5-(...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
D.A. Spandidos
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3673652/ https://ncbi.nlm.nih.gov/pubmed/23741254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2012.774 |
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