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Click dimers to target HIV TAR RNA conformation
A series of neomycin dimers have been synthesized using “Click chemistry” with varying functionality and length in the linker region to target the HIV-1 TAR RNA region of HIV virus. TAR (Transactivation Response) RNA region, a 59 base pair stem loop structure located at 5′-end of all nascent viral t...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3673543/ https://ncbi.nlm.nih.gov/pubmed/22339203 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi201657k |
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