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Pallidal neuronal discharge in Huntington’s disease: support for selective loss of striatal cells originating the indirect pathway
Chorea is the predominant motor manifestation in the early symptomatic phase of adult onset Huntington’s disease (HD). Pathologically, this stage is marked by differential loss of striatal neurons contributing to the indirect pathway. This pattern of neuronal loss predicts decreased neuronal firing...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3673313/ https://ncbi.nlm.nih.gov/pubmed/18342309 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2008.01.023 |
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