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Evidence for IL-1 receptor blockade as a therapeutic strategy for the treatment of depression

Uncontrollable stress, a major precipitant of depression in humans and in animal paradigms, impairs hippocampal neurogenesis, which is necessary for the behavioral effects of antidepressants in models of depression that require chronic treatment. However, the mechanisms underlying these anti-neuroge...

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Detalles Bibliográficos
Main Authors: Koo, Ja Wook, Duman, Ronald S
Formato: Artigo
Idioma:Inglês
Publicado: 2009
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3673287/
https://ncbi.nlm.nih.gov/pubmed/19579172
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