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Telomeres and age-related disease: how telomere biology informs clinical paradigms

Telomere length shortens with age and predicts the onset of replicative senescence. Recently, short telomeres have been linked to the etiology of degenerative diseases such as idiopathic pulmonary fibrosis, bone marrow failure, and cryptogenic liver cirrhosis. These disorders have recognizable clini...

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Autore principale: Armanios, Mary
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3673231/
https://ncbi.nlm.nih.gov/pubmed/23454763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI66370
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