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Telomeres and age-related disease: how telomere biology informs clinical paradigms

Telomere length shortens with age and predicts the onset of replicative senescence. Recently, short telomeres have been linked to the etiology of degenerative diseases such as idiopathic pulmonary fibrosis, bone marrow failure, and cryptogenic liver cirrhosis. These disorders have recognizable clini...

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Detalhes bibliográficos
Autor principal: Armanios, Mary
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3673231/
https://ncbi.nlm.nih.gov/pubmed/23454763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI66370
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