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rRNA:mRNA pairing alters the length and the symmetry of mRNA-protected fragments in ribosome profiling experiments

Motivation: Ribosome profiling is a new technique that allows monitoring locations of translating ribosomes on mRNA at a whole transcriptome level. A recent ribosome profiling study demonstrated that internal Shine–Dalgarno (SD) sequences have a major global effect on translation rates in bacteria:...

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Auteurs principaux: O’Connor, Patrick B. F., Li, Gene-Wei, Weissman, Jonathan S., Atkins, John F., Baranov, Pavel V.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3673220/
https://ncbi.nlm.nih.gov/pubmed/23603333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btt184
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