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Shimmer: detection of genetic alterations in tumors using next-generation sequence data
Motivation: Extensive DNA sequencing of tumor and matched normal samples using exome and whole-genome sequencing technologies has enabled the discovery of recurrent genetic alterations in cancer cells, but variability in stromal contamination and subclonal heterogeneity still present a severe challe...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3673219/ https://ncbi.nlm.nih.gov/pubmed/23620360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btt183 |
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