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Promoter-proximal CCCTC-factor binding is associated with an increase in the transcriptional pausing index

Motivation: It has been known for more than 2 decades that after RNA polymerase II (RNAPII) initiates transcription, it can enter into a paused or stalled state immediately downstream of the transcription start site before productive elongation. Recent advances in high-throughput genomic technologie...

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Bibliografische gegevens
Hoofdauteurs: Paredes, Sur Herrera, Melgar, Michael F., Sethupathy, Praveen
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3673211/
https://ncbi.nlm.nih.gov/pubmed/23047559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts596
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