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Proteomic profiling of human retinal pigment epithelium exposed to an advanced glycation-modified substrate
PURPOSE: The retinal pigment epithelium (RPE) and underlying Bruch’s membrane undergo significant modulation during ageing. Progressive, age-related modifications of lipids and proteins by advanced glycation end products (AGEs) at this cell–substrate interface have been implicated in RPE dysfunction...
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| Main Authors: | , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3673018/ https://ncbi.nlm.nih.gov/pubmed/22081232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00417-011-1856-9 |
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