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Ex vivo-expanded human regulatory T cells prevent the rejection of skin allografts in a humanised mouse model()

BACKGROUND: Composite tissue transplantation effectively reconstructs the most complex defects, but its use is limited due to harmful immunosuppression and the high susceptibility of skin to rejection. Development of tolerance is an ideal solution, and protocols using regulatory T cells (Tregs) to a...

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Main Authors: Issa, Fadi, Hester, Joanna, Goto, Ryoichi, Nadig, Satish, Goodacre, Tim E., Wood, Kathryn
格式: Artigo
語言:Inglês
出版: 2010
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672995/
https://ncbi.nlm.nih.gov/pubmed/21048528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0b013e3181ff8772
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