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A PEPTIDE ANTAGONIST DISRUPTS NATURAL KILLER CELL INHIBITORY SYNAPSE FORMATION(1)

Productive engagement of MHC Class I by inhibitory NK cell receptors depends on the peptide bound by the MHC class I molecule. Peptide:MHC complexes that bind weakly to killer cell immunoglobulin-like receptors (KIR) can antagonize the inhibition mediated by high affinity peptide:MHC complexes and c...

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Autors principals: Borhis, Gwenoline, Ahmed, Parvin S., Mbiribindi, Bérénice, Naiyer, Mohammed M., Davis, Daniel M, Purbhoo, Marco A, Khakoo, Salim I
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672982/
https://ncbi.nlm.nih.gov/pubmed/23382564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201032
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