Immunoglobulin-like transcript 7 (ILT7) but not bone marrow stromal cell antigen 2 (BST2, aka HM1.24, tetherin or CD317) modulates plasmacytoid dendritic cell function (pDC) in primary human blood leukocytes

The immunoglobulin-like transcript (ILT) 7 is a surface molecule selectively expressed by human plasmacytoid dendritic cells (pDCs). ILT7 cross-linking suppresses pDC activation and type I interferon (IFN-I) secretion following Toll-like receptors (TLR)7/9 engagement. The bone marrow stromal cell an...

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Detalhes bibliográficos
Main Authors: Tavano, Barbara, Galao, Rui Pedro, Graham, David R, Neil, Stuart JD, Aquino, Veronica N, Fuchs, Dietmar, Boasso, Adriano
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672947/
https://ncbi.nlm.nih.gov/pubmed/23401591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202391
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