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Connective tissue growth factor causes EMT-like cell fate changes in vivo and in vitro

Connective tissue growth factor (CTGF) plays an important role in the pathogenesis of chronic fibrotic diseases. However, the mechanism by which paracrine effects of CTGF control the cell fate of neighboring epithelial cells is not known. In this study, we investigated the paracrine effects of CTGF...

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Detalhes bibliográficos
Main Authors: Sonnylal, Sonali, Xu, Shiwen, Jones, Helen, Tam, Angela, Sreeram, Vivek R., Ponticos, Markella, Norman, Jill, Agrawal, Pankaj, Abraham, David, de Crombrugghe, Benoit
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672936/
https://ncbi.nlm.nih.gov/pubmed/23525012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.111302
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