Nanoscale Distribution of Ryanodine Receptors and Caveolin-3 in Mouse Ventricular Myocytes: Dilation of T-Tubules near Junctions

We conducted super-resolution light microscopy (LM) imaging of the distribution of ryanodine receptors (RyRs) and caveolin-3 (CAV3) in mouse ventricular myocytes. Quantitative analysis of data at the surface sarcolemma showed that 4.8% of RyR labeling colocalized with CAV3 whereas 3.5% of CAV3 was i...

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Bibliografiske detaljer
Main Authors: Wong, Joseph, Baddeley, David, Bushong, Eric A., Yu, Zeyun, Ellisman, Mark H., Hoshijima, Masahiko, Soeller, Christian
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2013
Fag:
Biophysical Letter
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672889/
https://ncbi.nlm.nih.gov/pubmed/23746531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.02.059
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