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Structural Flexibility of Ca(V)1.2 and Ca(V)2.2 I-II Proximal Linker Fragments in Solution

Voltage-dependent calcium channels (Ca(V)) enable the inward flow of calcium currents for a wide range of cells. Ca(V)1 and Ca(V)2 subtype α1 subunits form the conducting pore using four repeated membrane domains connected by intracellular linkers. The domain I-II linker connects to the membrane gat...

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書目詳細資料
Main Authors: Almagor, Lior, Avinery, Ram, Hirsch, Joel A., Beck, Roy
格式: Artigo
語言:Inglês
出版: The Biophysical Society 2013
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672870/
https://ncbi.nlm.nih.gov/pubmed/23746511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.04.034
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