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Conformational Determinants for the Recruitment of ERCC1 by XPA in the Nucleotide Excision Repair (NER) Pathway: Structure and Dynamics of the XPA Binding Motif
XPA is an essential protein in the nucleotide excision repair (NER) pathway, in charge of recruiting the ERCC1-XPF endonuclease complex to the DNA damage site. The only currently available structural insight into the binding of XPA to ERCC1 derives from the solution NMR structure of a complex betwee...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Biophysical Society
2013
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3672865/ https://ncbi.nlm.nih.gov/pubmed/23746523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.04.023 |
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