IL-17-mediated Bcl-2 expression regulates survival of fibroblast-like synoviocytes in rheumatoid arthritis through STAT3 activation

INTRODUCTION: Fibroblast-like synoviocytes (FLSs) are a major cell population of the pannus that invades adjacent cartilage and bone in rheumatoid arthritis (RA). The study was undertaken to determine the effect of interleukin-17 (IL-17) on the survival and/or proliferation of FLSs from RA patients...

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Détails bibliographiques
Auteurs principaux: Lee, Seon-Yeong, Kwok, Seung-Ki, Son, Hye-Jin, Ryu, Jun-Geol, Kim, Eun-Kyung, Oh, Hye-Jwa, Cho, Mi-La, Ju, Ji Hyeon, Park, Sung-Hwan, Kim, Ho-Youn
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2013
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Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672783/
https://ncbi.nlm.nih.gov/pubmed/23421940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4179
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