MRP8 promotes Th17 differentiation via upregulation of IL-6 production by fibroblast-like synoviocytes in rheumatoid arthritis

Myeloid-related protein (MRP)8/MRP14 is an endogenous Toll-like receptor 4 (TLR4) ligand and is abundant in synovial fluid (SF) of rheumatoid arthritis (RA) patients. Belonging to damage-associated molecular patterns, it amplifies proinflammatory mediators and facilitates a wide range of inflammator...

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Detalhes bibliográficos
Main Authors: Lee, Dong-Gun, Woo, Jung-Won, Kwok, Seung-Ki, Cho, Mi-La, Park, Sung-Hwan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3641402/
https://ncbi.nlm.nih.gov/pubmed/23619188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2013.39
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