HER2 and ESR1 mRNA expression levels and response to neoadjuvant trastuzumab plus chemotherapy in patients with primary breast cancer

INTRODUCTION: Recent data suggest that benefit from trastuzumab and chemotherapy might be related to expression of HER2 and estrogen receptor (ESR1). Therefore, we investigated HER2 and ESR1 mRNA levels in core biopsies of HER2-positive breast carcinomas from patients treated within the neoadjuvant...

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Detalhes bibliográficos
Main Authors: Denkert, Carsten, Huober, Jens, Loibl, Sibylle, Prinzler, Judith, Kronenwett, Ralf, Darb-Esfahani, Silvia, Brase, Jan C, Solbach, Christine, Mehta, Keyur, Fasching, Peter A, Sinn, Bruno V, Engels, Knut, Reinisch, Mattea, Hansmann, Martin-Leo, Tesch, Hans, von Minckwitz, Gunter, Untch, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672694/
https://ncbi.nlm.nih.gov/pubmed/23391338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3384
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