Extensive polymerase pausing during Drosophila axis patterning enables high-level and pliable transcription

Cascades of zygotic gene expression pattern the anterior–posterior (AP) and dorsal–ventral (DV) axes of the early Drosophila embryo. Here, we used the global run-on sequencing assay (GRO-seq) to map the genome-wide RNA polymerase distribution during early Drosophila embryogenesis, thus providing ins...

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Autori principali: Saunders, Abbie, Core, Leighton J., Sutcliffe, Catherine, Lis, John T., Ashe, Hilary L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2013
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672648/
https://ncbi.nlm.nih.gov/pubmed/23699410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.215459.113
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