Dopexamine can attenuate the inflammatory response and protect against organ injury in the absence of significant effects on hemodynamics or regional microvascular flow

INTRODUCTION: The effects of dopexamine, a β2-agonist, on perioperative and sepsis-related hemodynamic, microvascular, immune, and organ dysfunction are controversial and poorly understood. We investigated these effects in a rodent model of laparotomy and endotoxemia. METHODS: In two experiments, 80...

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Detalhes bibliográficos
Main Authors: Bangash, Mansoor N, Patel, Nimesh SA, Benetti, Elisa, Collino, Massimo, Hinds, Charles J, Thiemermann, Christoph, Pearse, Rupert M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672538/
https://ncbi.nlm.nih.gov/pubmed/23531318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc12585
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