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The adenine-thymine domain of the simian virus 40 core origin directs DNA bending and coordinately regulates DNA replication.

The simian virus 40 origin of replication contains a 20-base-pair adenine-thymine-rich segment with the sequence 5'-TGCATAAATAAAAAAAATTA-3'. The continuous tract of eight adenines is highly conserved among polyomaviruses. We used single-base substitutions to map structural and functional f...

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Detalhes bibliográficos
Main Authors: Deb, S, DeLucia, A L, Koff, A, Tsui, S, Tegtmeyer, P
Formato: Artigo
Idioma:Inglês
Publicado em: 1986
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC367242/
https://ncbi.nlm.nih.gov/pubmed/3025662
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