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The non-coding B2 RNA binds to the DNA cleft and active site region of RNA polymerase II

The B2 family of short interspersed elements is transcribed into non-coding RNA by RNA polymerase III. The ~180 nt B2 RNA has been shown to potently repress mRNA transcription by binding tightly to RNA polymerase II (Pol II) and assembling with it into complexes on promoter DNA, where it keeps the p...

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Detalhes bibliográficos
Main Authors: Ponicsan, Steven L., Houel, Stephane, Old, William M., Ahn, Natalie G., Goodrich, James A., Kugel, Jennifer F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672349/
https://ncbi.nlm.nih.gov/pubmed/23416138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.01.035
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